EthosEnergy CEO Ana Amicarella recognized as Top Executive for 2021

San Antonio, Texas, Oct. 19, 2021 (GLOBE NEWSWIRE) — San Antonio, Texas "" EthosEnergy's CEO, Ana Amicarella has been recognized as Top Executive of the Year during the Experience Power conference hosted by Power magazine.

Power magazine honored innovative leaders from the power generation industry during an awards ceremony at the Experience Power conference last night. A worldwide call for nominations went out and submissions were narrowed down to a shortlist of award–worthy contenders into 15 categories.

Ana Amicarella, CEO of EthosEnergy said: "I am honored to have won this award. But most of all, I am proud of everything our team has achieved over the last year despite challenging conditions."

Faced with outage cancellations and postponements due to COVID–19, and a depressed oil and gas sector, EthosEnergy's reaction was to restructure the business to better align with customers and market dynamics.

Ana Amicarella was appointed CEO in December 2019 with a mission to take EthosEnergy into its next stage of strategic development and position the company for growth. Prior to EthosEnergy, Ana spent 22 years with GE and eight with Aggreko, where she was managing director for the Latin America business.

In just one year Ana has led EthosEnergy through a revolutionary transformation. Despite the hurdles of COVID–19 and challenging market conditions, EthosEnergy achieved its best financial year to date and is on track for ambitious growth over the next five–years.

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About EthosEnergy

Our customers are facing a challenging future. They want a flexible and viable partner to support them in a world of changing expectations.

EthosEnergy turns on potential to deliver services and solutions globally for rotating equipment to make energy affordable, available and sustainable.

A unique combination of partnership and service quality, backed by a track record of tailored solutions, for the power, oil & gas, industrial and aerospace markets.

EthosEnergy operates in over 100 countries to consistently improve performance across the value chain.

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Adagio Therapeutics Announces New In Vitro Data Highlighting Broad and Potent Neutralization of ADG20 Against All Known SARS-CoV-2 Variants

WALTHAM, Mass., Oct. 19, 2021 (GLOBE NEWSWIRE) — Adagio Therapeutics, Inc., (Nasdaq: ADGI) a clinical–stage biopharmaceutical company focused on the discovery, development and commercialization of antibody–based solutions for infectious diseases with pandemic potential, today announced new in vitro data demonstrating retained neutralizing activity of its monoclonal antibody (mAb), ADG20, against a diverse panel of circulating SARS–CoV–2 variants, including the newly emerged Lambda and Mu variants. Notably, findings show that ADG20 demonstrated potent in vitro neutralizing activity against all SARS–CoV–2 variants of concern tested, including those with reduced susceptibility to mAb products currently available under Emergency Use Authorization (EUA) or in late–stage development. These data will be presented during a poster session at the 2021 ISIRV–WHO Virtual Conference, which is being held October 19–21, 2021. In addition, Adagio will present an encore poster highlighting recently announced data from the company's ongoing Phase 1 trial of ADG20 in healthy participants.

"These new variant data further underscore the potential of ADG20 to address the ongoing COVID–19 pandemic, as well as possible future outbreaks caused by other SARS–like viruses," said Laura Walker, Ph.D., co–founder and chief scientific officer of Adagio. "We have intentionally designed this mAb to have both broad and potent neutralizing activity as well as a half–life that extends its potential window of protection, critical features that may set it apart from other therapies available under EUA or in development today. With global Phase 2/3 prevention and treatment trials ongoing, we look forward to continuing our evaluation of ADG20 to assess the meaningful role it could potentially play in the arsenal of COVID–19 treatment options. Given as a single, intramuscular injection in clinical trials, ADG20 has been designed to offer protection for up to a year in the prevention setting and is being explored as a treatment for high–risk patients and/or as a vaccine supplement, including for immunocompromised individuals."

In addition to the Phase 1 healthy participant trial, Adagio is advancing two ongoing global Phase 2/3 trials with ADG20, a treatment trial (STAMP) and a prevention trial (EVADE). The company anticipates submitting an EUA application to the U.S. Food and Drug Administration for ADG20 in the first quarter of 2022.

Presentation Details
Poster Title: (130) Broad and Potent In Vitro Neutralization of SARS–CoV–2 Variants by ADG20, a Half–Life Extended Monoclonal Antibody in Development for the Prevention and Treatment of COVID–19

Poster Title: (131) Evaluating the Safety, Tolerability, and Pharmacokinetics of ADG20, a Half–Life""Extended Monoclonal Antibody (mAb) in Development for the Prevention and Treatment of COVID–19: a Preliminary Analysis of a Randomized Phase 1 Study

About ADG20
ADG20, a monoclonal antibody targeting the spike protein of SARS–CoV–2 and related coronaviruses, is being developed for the prevention and treatment of COVID–19, the disease caused by SARS–CoV–2. ADG20 was designed and engineered to possess high potency and broad neutralization against SARS–CoV–2 and additional clade 1 sarbecoviruses, by targeting a highly conserved epitope in the receptor binding domain. ADG20 displays potent neutralizing activity in vivo against the original SARS–CoV–2 strain as well as all known variants of concern. ADG20 has the potential to impact viral replication and subsequent disease through multiple mechanisms of action, including direct blocking of viral entry into the host cell (neutralization) and elimination of infected host cells through Fc–mediated innate immune effector activity. ADG20 is administered by a single intramuscular injection, and was engineered to have a long half–life, with a goal of providing both rapid and durable protection. Adagio is advancing ADG20 through multiple clinical trials on a global basis.

About Adagio Therapeutics
Adagio (Nasdaq: ADGI) is a clinical–stage biopharmaceutical company focused on the discovery, development and commercialization of antibody–based solutions for infectious diseases with pandemic potential. The company's portfolio of antibodies has been optimized using Adimab's industry–leading antibody engineering capabilities and is designed to provide patients and clinicians with a powerful combination of potency, breadth, durable protection (via half–life extension), manufacturability and affordability. Adagio's portfolio of SARS–CoV–2 antibodies includes multiple, non–competing broadly neutralizing antibodies with distinct binding epitopes, led by ADG20. Adagio has secured manufacturing capacity for the production of ADG20 with third–party contract manufacturers to support the completion of clinical trials and initial commercial launch, ensuring broad accessibility to people around the world. For more information, please visit www.adagiotx.com.

Forward Looking Statements
This press release contains forward–looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "anticipates," "believes," "expects," "intends," "projects," and "future" or similar expressions are intended to identify forward–looking statements. Forward–looking statements include statements concerning, among other things, the timing, progress and results of our preclinical studies and clinical trials of ADG20, including the timing of our planned EUA application, initiation and completion of studies or trials and related preparatory work, the period during which the results of the trials will become available and our research and development programs; our ability to obtain and maintain regulatory approvals for, our product candidates; our ability to identify patients with the diseases treated by our product candidates and to enroll these patients in our clinical trials; our manufacturing capabilities and strategy; and our ability to successfully commercialize our product candidates. We may not actually achieve the plans, intentions or expectations disclosed in our forward–looking statements and you should not place undue reliance on our forward–looking statements. These forward–looking statements involve risks and uncertainties that could cause our actual results to differ materially from the results described in or implied by the forward–looking statements, including, without limitation, those risks described under the heading "Risk Factors" in Adagio's Quarterly Report on Form 10–Q for the quarter ended June 30, 2021 and in Adagio's future reports to be filed with the SEC. Such risks may be amplified by the impacts of the COVID–19 pandemic. Forward–looking statements contained in this press release are made as of this date, and Adagio undertakes no duty to update such information except as required under applicable law.

Contacts:

Media Contact:
Dan Budwick, 1AB
Dan@1abmedia.com

Investor Contact:
Monique Allaire, THRUST Strategic Communications
monique@thrustsc.com


Inflation Bogey Blocking Recovery

By Anis Chowdhury and Jomo Kwame Sundaram
SYDNEY and KUALA LUMPUR, Oct 19 2021 - The bogey of inflation has been revived. Dubious pre-pandemic economic progress, fiscal constraints and vaccine apartheid were bad enough. Now, ostensibly [...] Read more »