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Janet D’Addario, Co-Founder of D’Addario & Co., and Former President of Providence House, Dies at 72.

FARMINGDALE, N.Y., June 17, 2021 (GLOBE NEWSWIRE) — Janet D'Addario, a prodigious creative and philanthropic force throughout the world, and wife of D'Addario Chairman, Jim D'Addario, died on June 14th in her home, surrounded by her entire family. She was 72.

The cause was complications from gall bladder cancer, said her husband, Jim D'Addario.

Janet Marie D'Addario was born on December 10th, 1948 in Nassau County. Her education circumnavigated Long Island: St. Brigid in Westbury; St. Dominic's High School in Oyster Bay, and Nassau Community College in Garden City.

In 1966, the course of her life would forever change when the 18–year–old lead singer of a folk group met another young, budding musician who was instantly smitten by her tender voice and magnetic personality. Jim and Janet D'Addario would go on to marry, sing and perform on stage together, and start an extraordinary 50–year partnership that produced a family, a philanthropic legacy, and the most prestigious music accessories business in the world.

When D'Addario & Co. was first founded in 1973, Janet used her creative talents to design the company's advertising as well as the packaging design for all of their products. As a fledgling organization, Janet's vision and compassion had a tremendous influence on the development of the culture that guides the organization today.

She would go on to wear many hats, including head of Artist Relations and co–founder of the D'Addario Foundation, which continues to provide music education to young children in underserved communities. Janet served as the Managing Director of the Foundation for 20 years""helping to raise awareness for the cause by producing classical music concerts in cities around the world.

Ms. D'Addario was known by family and friends for her peerless compassion and generosity""fervently believing that actions mean far more than just words. She would go on to serve 11 years on the Board of Long Island Cares, the charity created by Harry Chapin to eradicate hunger on Long island. As a devout Catholic, she supported numerous Catholic charities across the globe, the Long Island Catholic Hospital system as well as her own, personal parish, St. Brigid.

The one charity that held a particularly special place in her heart was Providence House, a New York institution that provides transitional housing for homeless women and children.

"Providence House is, in so many ways, the very embodiment of my wife…when she saw pain, she wanted to ease it. When she saw hunger, she brought food. When she saw homelessness, she provided shelter. But most importantly when Janet saw someone with no hope, she worked hard to provide them with the tools to restore their will to overcome the challenges they were facing.," said Jim D'Addario.

Ms. D'Addario served as a Board Member of Providence House for 21 years and as its President from 2004–2019. Over those years, she helped raise millions of dollars to ensure thousands of women and children would have a pathway to a brighter future. Her invaluable work led to Janet and Jim being named the first People of Hope in 2002 and the construction of the 43–unit D'Addario Residence in Bedford Stuyvesant, Brooklyn.

In addition to her philanthropic work, Janet was an avid foodie and prolific painter. Not surprisingly, her greatest joy was bringing friends and family together for a homemade meal and the occasional musical performance by she and Jim, as well as their many musical friends.

Janet D'Addario was the daughter of Robert James Carbone and Annabelle (Eannaccone) Carbone of Westbury, New York. She is survived by her loving husband of over 50 years, Jim D'Addario, and their three children: Julie (Pat); Amy (Marcus) and Robert (Gina). She is also survived by eight grandchildren, and her beloved dogs, Dave and Blue.

In lieu of any gifts or flowers, the family is asking anyone wishing to pay their respects to consider a modest donation to Providence House (https://www.providencehouse.org/support–our–work).

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/88f5885b–1766–4876–89ab–810766a28ed6


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Entera Bio Receives Foundational Patent for its Oral PTH using its Platform Oral Protein Delivery Technology in European Union

"' Oral delivery technology has potential to transform $20 billion injectable biologics market "'

"' Final BMD results from company's Phase 2 Osteoporosis study of EB 613 expected in Q2/2021 "'

BOSTON and JERUSALEM, June 17, 2021 (GLOBE NEWSWIRE) — Entera Bio Ltd. (NASDAQ: ENTX), a leader in the development of orally delivered large molecule therapeutics, today announced the European Patent Office has granted a patent titled "Methods and Compositions for Oral Administration of Proteins" to Entera. The patent addresses Entera's oral PTH formulations currently in advanced clinical stages for osteoporosis and hypoparathyroidism.

"This is a critical patent that covers lead PTH products utilizing Entera's platform technology. This European Union patent, along with a variety of other patents covering oral formulations and target indications, granted and pending, provide Entera with robust protection of its intellectual property. This granted patent comes in addition to numerous issued patents in strategic countries including the USA, China, Japan, Australia, New Zealand and Israel. We are particularly pleased to have successfully completed the nine–month time window in which the patent could have been opposed. Entera has fortified its leadership position in the oral delivery of proteins as we look forward to reporting the full 6 month BMD results from our Phase 2 study, as planned this Q2/2021 and potentially initiating a pivotal Phase 3 study with our oral PTH for the treatment of osteoporosis next year," stated Entera CEO Spiros Jamas. "We continuously strive to strengthen our portfolio with new patents addressing specific applications as well as novel improvements to our platform."

About Entera Bio

Entera is a leader in the development of orally delivered large molecule therapeutics for use in areas with significant unmet medical need where adoption of injectable therapies is limited due to cost, convenience and compliance challenges for patients. The Company's proprietary, oral drug delivery technology is designed to address the technical challenges of poor absorption, high variability, and the inability to deliver large molecules to the targeted location in the body through the use of a synthetic absorption enhancer to facilitate the absorption of large molecules, and protease inhibitors to prevent enzymatic degradation and support delivery to targeted tissues. The Company's most advanced product candidates, EB613 for the treatment of osteoporosis and EB612 for the treatment of hypoparathyroidism are in Phase 2 clinical development. Entera also licenses its technology to biopharmaceutical companies for use with their proprietary compounds and, to date, has established a collaboration with Amgen Inc. For more information on Entera Bio, visit www.enterabio.com.

Forward Looking Statements

Various statements in this release are "forward–looking statements" under the securities laws. Words such as, but not limited to, "anticipate," "believe," "can," "could," "expect," "estimate," "design," "goal," "intend," "may," "might," "objective," "plan," "predict," "project," "target," "likely," "should," "will," and "would," or the negative of these terms and similar expressions or words, identify forward–looking statements. Forward–looking statements are based upon current expectations that involve risks, changes in circumstances, assumptions and uncertainties. Forward–looking statements should not be read as a guarantee of future performance or results and may not be accurate indications of when such performance or results will be achieved.

Important factors that could cause actual results to differ materially from those reflected in Entera's forward–looking statements include, among others: changes in our interpretation of the complete 3–month biomarker data from the ongoing Phase 2 clinical trial of EB613, the timing of data readouts from the ongoing Phase 2 clinical trial of EB613, the full results of the Phase 2 clinical trial of EB613, which is still ongoing and our analysis of those full results, the FDA's interpretation and review of our results from and analysis of our Phase 2 trial of EB613, unexpected changes in our ongoing and planned preclinical development and clinical trials, the timing of and our ability to make regulatory filings and obtain and maintain regulatory approvals for our product candidates; a possible suspension of the Phase 2 clinical trial of EB613 for clinical or data–related reasons; the impact of COVID–19 on Entera's business operations including the ability to collect the necessary data from the Phase 2 trial of EB613; the potential disruption and delay of manufacturing supply chains, loss of available workforce resources, either by Entera or its collaboration and laboratory partners, due to travel restrictions, lay–offs or forced closures or repurposing of hospital facilities; impacts to research and development or clinical activities that Entera is contractually obligated to provide, such as those pursuant to Entera's agreement with Amgen; overall regulatory timelines, if the FDA or other authorities are closed for prolonged periods, choose to allocate resources to review of COVID–19 related drugs or believe that the amount of Phase 2 clinical data collected are insufficient to initiate a Phase 3 trial, or a meaningful deterioration of the current political, legal and regulatory situation in Israel or the United States; the availability, quality and timing of the data from the Phase 2 clinical trial of EB613 in osteoporosis patients; the ability to find a dose that demonstrates the comparability of EB613 to FORTEO in the ongoing Phase 2 clinical trial of EB613; the size and growth of the potential market for EB613 and Entera's other product candidates including any possible expansion of the market if an orally delivered option is available in addition to an injectable formulation; the scope, progress and costs of developing Entera's product candidates including EB612 and GLP–2; Entera's reliance on third parties to conduct its clinical trials; Entera's expectations regarding licensing, business transactions and strategic collaborations; Entera's operation as a development stage company with limited operating history; Entera's ability to continue as a going concern absent access to sources of liquidity; Entera's expectations regarding its expenses, revenue, cash resources, liquidity and financial condition; Entera's ability to raise additional capital; Entera's interpretation of FDA feedback and guidance and how such guidance may impact its clinical development plans; Entera's ability to obtain and maintain regulatory approval for any of its product candidates; Entera's ability to comply with Nasdaq's minimum listing standards and other matters related to compliance with the requirements of being a public company in the United States; Entera's intellectual property position and its ability to protect its intellectual property; and other factors that are described in the "Special Note Regarding Forward–Looking Statements," "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" sections of Entera's annual and current filings which are on file with the SEC and available free of charge on the SEC's website at http://www.sec.gov. Additional factors may be set forth in those sections of Entera's Annual Report on Form 20–F for the year ended December 31, 2020, filed with the SEC in the first quarter of 2021. In addition to the risks described above and in Entera's annual report on Form 20–F and current reports on Form 6–K and other filings with the SEC, other unknown or unpredictable factors also could affect Entera's results. There can be no assurance that the actual results or developments anticipated by Entera will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, Entera. Therefore, no assurance can be given that the outcomes stated in such forward–looking statements and estimates will be achieved.

All written and verbal forward–looking statements attributable to Entera or any person acting on its behalf are expressly qualified in their entirety by the cautionary statements contained or referred to herein. Entera cautions investors not to rely too heavily on the forward–looking statements Entera makes or that are made on its behalf. The information in this release is provided only as of the date of this release, and Entera undertakes no obligation, and specifically declines any obligation, to update or revise publicly any forward–looking statements, whether as a result of new information, future events or otherwise.


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