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Angelini Pharma Announces Appointment of Sergio Marullo di Condojanni as New CEO

ROME, Jan. 21, 2026 (GLOBE NEWSWIRE) — Angelini Pharma, part of the multinational privately owned industrial group Angelini Industries, today announced the appointment of Sergio Marullo di Condojanni as Chief Executive Officer. He has served as CEO of Angelini Industries since 2020 and will maintain that role while assuming leadership of the pharmaceutical division to drive cohesive strategy implementation, leveraging extensive executive, governance, and financial expertise. Jacopo Andreose, who led Angelini Pharma until the end of 2025, will become a member of the Angelini Holding board and a senior advisor to the Angelini Pharma board.

The appointment is part of Angelini Industries’ multi–year effort to strengthen its corporate governance and operating model, building on the Group's century–long heritage of pharmaceutical excellence. The transition aims to further solidify pharmaceutical healthcare as a core pillar of its long–term growth strategy alongside industrial technology.

Thea Paola Angelini, Chair of Angelini Holding and majority shareholder, stated:
“Appointing Sergio as CEO will drive simplified decision–making for our pharmaceutical business — the heart of our Group. This strategic choice will enable us to be closer to market needs and, above all, to patients, by delivering greater efficiency, agility, faster decision–making, and flexibility.”

Marullo di Condojanni’s dual role will enable him to directly spearhead strategy implementation within the healthcare division, seeking to maximize the value of Angelini Pharma in a high–growth sector. He will focus on further elevating the company’s leadership in Brain Health, with particular attention to rare neurological diseases, while continuing to build on its legacy in Consumer Healthcare. He will also prioritize expanding Angelini Pharma’s global reach, including additional acquisitions to strengthen its pipeline of innovative medicines and promising candidates. The emphasis remains on sustaining investment in research, development, and manufacturing operations in Italy, while simultaneously turning outwardly for commercial expansion opportunities on the international scale.

“I am excited and deeply honored to take on this important role at the helm of Angelini Pharma during a pivotal moment of transformation,” said Sergio Marullo di Condojanni. “Our strategic priorities are clear: strengthen long–term competitiveness and seize transformative M&A opportunities that will enable us to scale globally. At the same time, our focus will be on driving our ambitious strategy to achieve market leadership and deliver breakthrough solutions in brain health for patients worldwide.”

As Angelini Industries’ CEO, Sergio Marullo di Condojanni oversaw record revenue growth, expanding the Group to 21 countries and €1.6 billion* in revenue, and successfully launched Angelini Ventures, the Group's €300 million corporate venture capital dedicated to biotech and medtech. Prior to Angelini Industries, his extensive background included influential roles in the Italian financial sector, such as Chairman of the Territorial Committee of Banco BPM, and a key appointment to the Advisory Board of the G20 Business Summit Italy 2021. He holds a Ph.D. in Domestic and International Arbitration, is a Full Professor of Private Law, and serves on the Board of Directors for institutions including the Fondazione Istituto Italiano di Tecnologia.

Under his leadership, Angelini Pharma will accelerate its strategy to become a global leader in Brain Health. The company has significantly strengthened its pipeline, diversifying into innovative therapeutic modalities that include small molecules, biologics, and anti–sense oligonucleotides. Most recently, Angelini Pharma signed an exclusive option agreement with Sovargen for the antisense oligonucleotide SVG1051 in September 2025. Other recent strategic deals include the May 2025 collaboration announcement with GRIN Therapeutics for the investigational drug radiprodil, and rights secured for OmniAb's preclinical asset RO'599. Further reinforcing the pipeline are a partnership with Cureverse for the Nrf2–targeting compound CV–01 (since 2024), and a collaboration with JCR Pharmaceuticals, which leverages their proprietary J–Brain Cargo® technology to develop novel brain–penetrant biologic therapies for epilepsy (since 2023).

The new strategic vision will be supported by a new organizational structure that establishes dedicated franchises aiming to maximize value creation and support international expansion into high–growth regions.

About Brain Health
Brain health as a therapeutic area includes both neurological and mental health conditions.1 Brain health is defined by the World Health Organization as a state of brain functioning across cognitive, sensory, social–emotional, behavioral and motor domains, allowing a person to realize their full potential over the course of their life, irrespective of the presence or absence of disorders.2

Brain health represents an urgent global health priority. An estimated 179 million Europeans are living with brain health conditions3 and more than 18% of all health loss around the world is associated with brain conditions.4 Additionally, brain health conditions are responsible for considerable individual, economic and societal impact, including loss of independence, reduced productivity, strained relationships, increased risk of suicide as well as high healthcare costs.5 There is an urgent need to raise awareness, and reduce stigma, prejudice and discrimination, to ensure that brain health is valued, promoted and protected for all.2

About Epilepsy

Epilepsy is one of the most widespread neurological diseases in the world, affecting globally approximately 50 million people of all ages.6 In Europe, up to six million people are estimated to be living with this disease.7 Epilepsy can have multiple potential causes, including structural, metabolic, genetic and other factors, though approximately half of cases worldwide do not have a known cause.6

The complications associated with epilepsy are severe, with a risk of premature mortality up to three times higher than the general population.6 The recurrent seizures associated with this condition also have wide–ranging effects on a person’s broader physical and mental health, education and employment opportunities and other quality of life factors.6

Treatments are available to help reduce seizures and improve quality of life, however approximately 40% of people living with epilepsy are still uncontrolled despite the treatment with two anti–seizure medications.8

About Angelini Pharma
Angelini Pharma is an international pharmaceutical company, part of the privately owned multi–business Angelini Industries. The Company researches, develops and commercializes health solutions with a focus on the areas of Brain Health, including Mental Health and Epilepsy, and Consumer Health. Founded in Italy at the beginning of the 20th century, Angelini Pharma operates directly in 20 countries, employing more than 3,000 people. Its products are marketed in over 70 countries through strategic alliances with leading international pharmaceutical groups. For more information about Angelini Pharma please visit: https://www.angelinipharma.com.

About Angelini Industries
Angelini Industries is a multinational industrial group founded in Ancona in 1919 by Francesco Angelini. Today, it represents a solid and diversified industrial entity employing around 5,600 people operating in 21 countries worldwide, with revenues of €1.6 billion. Angelini Industries operates in the Health, Industrial Technology and Consumer Goods sectors. Led by the Angelini family for over 100 years, the industrial group is distinguished by an investment strategy focused on growth, a governance model that combines the long–term vision of family–owned businesses with the practices of publicly listed companies, in–depth knowledge of markets and business sectors, and a commitment to promoting sustainable growth for people, communities, ecosystems, and the planet. To learn more, please visit www.angeliniindustries.com.

Contact                
Chiara Antoniucci
Global Head of Brand and Media Communications, Angelini Pharma
+39 3477133926
[email protected]

______________________________

*According to International Financial Reporting Standards (IFRS) for the fiscal year ending December 31, 2024

1 Winkler AS, et al. Lancet Glob Health. 2024;12(5):e735–e736.
2 World Health Organization. Optimizing brain health across the life course: WHO position paper. Geneva: World Health Organization; 2022.
3 Nutt D, et al. Eurohealth (Int) 2017;23:21–5.
4 Institute for Health Metrics and Evaluation. Understanding brain health around the world. Available at: https://brainhealthatlas.org/. Accessed November 2025.
5 World Health Organization. World mental health report: transforming mental health for all. Geneva: World Health Organization; 2022.
6 World Health Organization. “Epilepsy Key Facts.” N.p., 9 Feb. 2023. Web. 24 Aug. 2023.
7 Behr et al. Epidemiology of epilepsy. Revue Neurologique 2016 Jan; 172(1):27–36.
8 Chen Z, et al. JAMA Neurol. 2018 Mar 1;75(3):279–286.

MAT–UKI–0398–NP | December 2025


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Angelini Pharma Signs Exclusive Option Agreement With Sovargen To License Global Development and Commercialization Rights For Innovative Brain Health Asset

  • Angelini Pharma secures exclusive option to license global development and commercialization rights for SVG1051, a pre–clinical investigational novel compound with broad potential to treat brain health diseases, excluding the Republic of Korea, China, Hong Kong, Macau and Taiwan
  • Sovargen receives upfront payment and is eligible for future milestone–dependent payments and royalties
  • Agreement further expands Angelini Pharma’s strong portfolio and deep therapeutic expertise in brain health, following a series of strategic partnerships in the space, including in orphan and rare epilepsy

ROME, Sept. 22, 2025 (GLOBE NEWSWIRE) — Angelini Pharma, part of the privately owned Angelini Industries, and Sovargen, a South–Korean biotechnology company, announced today that they signed an exclusive global option agreement for the development and commercialization of Sovargen’s innovative brain health asset SVG105.

Under the terms of the agreement, Angelini Pharma and Sovargen will collaboratively lead the pre–clinical development efforts for SVG105 and, following an initial option period, Angelini Pharma will have the right to advance the compound into clinical development and commercialization outside of the Republic of Korea, China, Hong Kong, Macau and Taiwan. SVG105 is a potentially first–in–class anti–sense oligonucleotide technology to target mTOR (mammalian target of rapamycin) pathways. mTOR is a genetically validated target for a number of brain health disorders, including drug–resistant childhood epilepsy.i

Sovargen will receive an upfront payment and will also be eligible to receive additional payments upon pre–defined development and commercial milestones of up to approx. US$550 million, as well as tiered royalties on post–approval net sales.

The announcement follows a number of strategic acquisitions and collaboration agreements that Angelini Pharma has entered over the course of the past two years, which have bolstered the company’s pipeline in brain health, adding to its strong portfolio in the space through sustained investment. In May 2025, Angelini Pharma and GRIN Therapeutics Inc. announced a collaboration for the development and commercialization rights outside of North America for radiprodil, an investigational drug currently being studied in multiple rare genetic epilepsies and neurodevelopmental disorders. A few days earlier, the company signed an asset purchase and assignment agreement for the development and commercialization of OmniAb’s innovative preclinical asset RO’599, a novel preclinical–stage investigational compound with broad potential to treat various brain health diseases. Last year, Angelini Pharma entered into a strategic partnership with Cureverse, a Korean spin–off of the Korean Institute of Science and Technology, which is developing small molecules with broad CNS applications. In 2023, the company partnered with JCR Pharmaceuticals, a Japanese biotech company with a breakthrough blood–brain barrier technology based on a transferrin receptor mechanism, allowing biologics to cross the barrier. Consequently, Angelini’s brain health pipeline now includes diversified and modern therapeutic modalities ranging from innovative small molecule compounds to biologics and anti–sense oligonucleotides.

“This partnership with Sovargen further solidifies Angelini Pharma’s leading role in the field of brain health, adding additional breadth to our robust portfolio and pipeline,” said Jacopo Andreose, Chief Executive Officer of Angelini Pharma. “Neurological disorders like epilepsy are major contributors to global disease challenges.ii For example, many people living with epilepsy are still unable to reach seizure control despite combination treatment of several anti–seizure medications.iii Our work on SVG105 will be motivated by the ambition to bring much–needed solutions to people living with brain health conditions across the world.”

“We are incredibly excited about the opportunity to work with Angelini Pharma to further advance SVG105,” said Cheolwon Park, Chief Executive Officer at Sovargen. “Our research so far demonstrates great potential for SVG105 to transform the treatment landscape in brain health and we are confident that Angelini Pharma’s strong therapeutic expertise will propel our research further and bring us closer to identifying new treatment options for patients in need.”

Brain Health
Brain health as a therapeutic area includes both neurological and mental health conditions.iv Brain health is defined by the World Health Organization as a state of brain functioning across cognitive, sensory, social–emotional, behavioral and motor domains, allowing a person to realize their full potential over the course of their life, irrespective of the presence or absence of disorders.v

Brain health represents an urgent global health priority. An estimated 179 million Europeans are living with brain health conditionsvi and more than 18% of all health loss around the world is associated with brain conditions.vii Additionally, brain health conditions are responsible for considerable individual, economic and societal impact, including loss of independence, reduced productivity, strained relationships, increased risk of suicide as well as high healthcare costs.viii There is an urgent need to raise awareness, and reduce stigma, prejudice and discrimination, to ensure that brain health is valued, promoted and protected for all.v

Epilepsy

Epilepsy is one of the most widespread neurological diseases in the world, affecting globally approximately 50 million people of all ages.ix In Europe, up to six million people are estimated to be living with this disease.x Epilepsy can have multiple potential causes, including structural, metabolic, genetic and other factors, though approximately half of cases worldwide do not have a known cause.ix

The complications associated with epilepsy are severe, with a risk of premature mortality up to three times higher than the general population.ix The recurrent seizures associated with this condition also have wide–ranging effects on a person’s broader physical and mental health, education and employment opportunities and other quality of life factors.ix

Treatments are available to help reduce seizures and improve quality of life, however approximately 40% of people living with epilepsy are still uncontrolled despite the treatment with two anti–seizure medications.iii

Angelini Pharma
Angelini Pharma is an international pharmaceutical company, part of the privately owned multi–business Angelini Industries. The Company researches, develops and commercializes health solutions with a focus on the areas of Brain Health, including Mental Health and Epilepsy, and Consumer Health. Founded in Italy at the beginning of the 20th century, Angelini Pharma operates directly in 20 countries, employing more than 3,000 people. Its products are marketed in over 70 countries through strategic alliances with leading international pharmaceutical groups. More information: https://www.angelinipharma.com.

Angelini Industries
Angelini Industries is a multinational industrial group founded in Ancona in 1919 by Francesco Angelini. Today, Angelini Industries represents a solid and diversified industrial reality that employs approximately 5,800 employees and operates in 21 countries around the world with revenues of over 2 billion euros, generated in the health, industrial technology, and consumer goods sectors. A targeted investment strategy for growth; constant commitment to research and development; deep knowledge of markets and business sectors, make Angelini Industries one of the Italian companies of excellence in the sectors in which it operates. More information: www.angeliniindustries.com.

Sovargen
Founded in 2018, Sovargen is a Korean biotech company pioneering treatments for intractable brain diseases caused by somatic mutations—genetic changes acquired during brain development or aging. These mutations underlie serious conditions like focal cortical dysplasia (FCD) type II, hemimegalencephaly, and brain tumors, yet remain largely unaddressed.

Sovargen’s proprietary antisense oligonucleotide (ASO) platform enables precise gene modulation in the brain. Its lead program, SVG105, is a first–in–disease ASO therapy in preclinical development for drug–resistant epilepsy caused by FCD type II. With a growing pipeline and a differentiated scientific approach, Sovargen is advancing next–generation CNS therapies to bring new hope to patients worldwide. More information: www.sovargen.com.

Contact                
Chiara Antoniucci
Global Head of Brand and Media Communications, Angelini Pharma
+39 3477133926
[email protected]

Rosie JH Lee
Director of Corporate PR, Sovargen
+82–70–5222–2771
[email protected]

1 SVG105 is an investigational compound, not approved for use by regulatory authorities.

i Data on file (Sovargen).
ii Institute for Health Metrics and Evaluation (IHME). Global burden of conditions affecting the nervous system. Available at: https://www.healthdata.org/research–analysis/library/global–burden–conditions–affecting–nervous–system Last accessed: July 2025.
iii Chen Z, Brodie MJ, Liew D, Kwan P. Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30–Year Longitudinal Cohort Study. JAMA Neurol. 2018 Mar 1;75(3):279–286.
iv Winkler AS, et al. Lancet Glob Health. 2024;12(5):e735–e736.
v WHO. Optimizing brain health across the life course: WHO position paper. Geneva: World Health Organization; 2022.
vi Nutt D, et al. Eurohealth (Int) 2017;23:21–5.
vii IHME. Understanding brain health around the world. Available at: https://brainhealthatlas.org/ Last accessed: July 2025.
viii WHO. World mental health report: transforming mental health for all. Geneva: World Health Organization; 2022.
ix WHO. “Epilepsy Key Facts.” N.p., 9 Feb. 2023. Web. 24 Aug. 2023.
x Behr et al. Epidemiology of epilepsy. Revue Neurologique 2016 Jan; 172(1):27–36. doi: 10.1016/j.neurol.2015.11.003.


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